Oil-based adjuvants

The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Gallo, Guillermo, Foss, Dennis L, Mwangi, Duncan, Donachie, William, Smith, David George Emslie, Dominowski, Paul Joseph, Vora, Shaunak, Mahan, Suman, Rai, Sharath K, Krebs, Richard Lee, Hardham, John Morgan, Mediratta, Sangita, Salmon, Sarah A, Mohr, Kaori, Lightle, Sandra Ann Marie, Jaglarz, Anita Dorota, Wilmes, Lauren, Fontaine, Michael Christopher, Fitzpatrick, Julie Lydia
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.