Ophthalmic implants with extended depth of field and enhanced distance visual acuity

A first and second lens together defining a lens pair configured for implantation into a first eye and a second eye, respectively, of a subject to provide modified monovision, comprising: the first lens configured to have positive depth of field, the first lens comprising: an optic comprising transparent material, the optic of the first lens having an anterior surface and a posterior surface, the anterior surface comprising an aspheric surface, wherein the anterior and posterior surfaces of said first lens are shaped to provide average modulation transfer function (MTF) values that are between 0.1 and 0.4 at 100 lines per millimetre for at least 90% of the object vergences within the range of 0 to 2.0 D or 0 to 2.5 D when said optic of said first lens is inserted into a model eye having an aperture size from 4 to 6 millimetres, wherein said average MTF values of said first lens comprise MTF values at 100 lines per millimetre integrated over the wavelengths between about 400 to 700 nm weighted by the photopic luminosity function for on axis objects, and the second lens configured to have negative depth of field, the second lens comprising: an optic comprising transparent material, said optic of said second lens having an anterior surface and a posterior surface, said anterior surface comprising an aspheric surface, wherein the anterior and posterior surfaces of said second lens are shaped to provide average modulation transfer function (MTF) values that are between 0.1 and 0.4 at 100 lines per millimetre for at least 90% of the object vergences within the range of -2.0 to 0 D or -2.5 to 0 D when said optic of said second lens is inserted into the model eye having an aperture size from 4 to 6 millimetres, wherein said average MTF values of said second lens comprise MTF values at 100 lines per millimetre integrated over the wavelengths between about 400 to 700 nm weighted by the photopic luminosity function for on axis objects, such that when the first and second lenses are implanted in a first eye and a second eye, respectively, of a subject, the positive depth of field of the first lens provides the subject an extended depth of field in the direction of nearer objects, and the negative depth of field of the second lens provides the subject an extended depth of field in the direction of more distant objects. WO 2016/040331 PCT/US2015/048961 205c 295d TIjC.2