HUMANIZATION OF RABBIT ANTIBODIES USING A UNIVERSAL ANTIBODY FRAMEWORK

The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, using a universal antibody acceptor framework. Antibodies 5 generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.

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Bibliographische Detailangaben
Hauptverfasser:	Borras, Leonardo, Urech, David
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, using a universal antibody acceptor framework. Antibodies 5 generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.