Recombinant chorionic gonadotropin, procedure for preparation, pharmaceutical compositions and uses of the same

This invention relates to a recombinant single chain chorionic gonadotropin polypeptide, having an amino acid sequence encoding the beta chain and the alpha chain of the equine chorionic gonadotropin linked to one or more sequences that include glycosylation sites, which results in excellent in vitro and in vivo activity. The DNA molecules that encode the recombinant polypeptide are also taught, an expression vector comprising these DNA molecules, compositions comprising the recombinant protein and methods for preparing them are also disclosed.