Crystalline forms of nicotinoyl ribosides and derivatives thereof, and methods of preparation thereof

The present disclosure provides crystalline Form II of nicotinic acid riboside, crystalline Form II of nicotinic acid riboside triacetate, and methods of preparation thereof. In an embodiment, the present disclosure relates to crystalline forms of nicotinoyl ribosides, derivatives thereof, or salts,...

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Hauptverfasser: STORJOHANN, Amanda, REDPATH, Philip, HOLLOWAY, Joshua, RHONEMUS, Troy, ERICKSON, Aron
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides crystalline Form II of nicotinic acid riboside, crystalline Form II of nicotinic acid riboside triacetate, and methods of preparation thereof. In an embodiment, the present disclosure relates to crystalline forms of nicotinoyl ribosides, derivatives thereof, or salts, hydrates, solvates, or prodrugs thereof. In another embodiment, the present disclosure relates to synthetic sequences or processes that enable the efficient production of crystalline forms of nicotinoyl ribosides, derivatives thereof, or salts, hydrates, solvates, or prodrugs thereof.