CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer

CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer

A crystalline form and/or polymorph of a compound having the following structure (I), including tautomeric and zwitterionic forms thereof, are provided: Methods associated with preparation and use of the polymorphs, and pharmaceutical compositions comprising the same are also provided. Also provided...

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Bibliographische Detailangaben
Hauptverfasser: TANAKA, Hiroaki, SIDDIQUI-JAIN, Adam, FLYNN, Paul, FUJIWARA, Yuji, HASHIZUKA, Takahiko, MASUMOTO, Shuji, KUREBAYASHI, Hirotaka, ARIKAWA, Yuka
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A crystalline form and/or polymorph of a compound having the following structure (I), including tautomeric and zwitterionic forms thereof, are provided: Methods associated with preparation and use of the polymorphs, and pharmaceutical compositions comprising the same are also provided. Also provided are methods for preparing a compound having formula (I), or a salt, tautomer or zwitterionic form thereof.