Methods and systems for determining a physiological or biological state or condition of a subject

The present disclosure provides methods, devices, and systems for determining a state or condition of a subject. A method for determining a state or condition of a heart of a subject may include using a monitoring device comprising an electrocardiogram (ECG) sensor and an audio sensor to measure ECG data and audio data from an organ of the subject, and transmitting the ECG data and the audio data wirelessly to a computing device. A trained algorithm may be used to process the ECG data and the audio data to determine the state or condition of the organ of the subject. More specifically, the trained algorithm can be customized for a specific indication or condition. An output indicative of the state or condition of the heart of the subject may be provided on the computing device.