Method for preparing 2-((3R)-3-methylmorpholin-4-yl)-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine

Method for preparing 2-((3R)-3-methylmorpholin-4-yl)-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine

The present invention covers a method for preparing 2-[(3R)-3- methylmorpholin-4-yl]-4-(1-methyl-1 H-pyrazol-5-yl)-8-(1 H-pyrazol-5- yl)-1,7-naphthyridine ("the compound of formula (I)" in the following) as well as intermediate compounds useful in the preparation of the compound of formula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HOOGEVEEN, Sonja, GIELING, Reinerus Gerardus, RUBENBAUER, Philipp, VAN OERS, Matthijs Cornelis Maria, PLATZEK, Johannes, VAN DER HAAS, Hendricus Nicolaas Sebastiaan, DEKKER, Jeroen Alexander
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention covers a method for preparing 2-[(3R)-3- methylmorpholin-4-yl]-4-(1-methyl-1 H-pyrazol-5-yl)-8-(1 H-pyrazol-5- yl)-1,7-naphthyridine ("the compound of formula (I)" in the following) as well as intermediate compounds useful in the preparation of the compound of formula (I). The present invention also covers polymorphic form B of the compound of formula (I) with very high purity.