Protein recognizing drug moiety of antibody-drug conjugate

A protein that recognizes the drug moiety of an antibody-drug conjugate in which a drug represented by the formula is linked to an antibody via a linker; a method for measuring the concentration of the antibody-drug conjugate in the plasma of a mammal dosed with the antibody-drug conjugate using the...

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Bibliographische Detailangaben
Hauptverfasser:	KAWAMURA, Junko, ISHIBASHI, Hiromi, SOMA, Masako, MASUDA, Takeshi, YASUDA, Satoru, KUGA, Hiroshi
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A protein that recognizes the drug moiety of an antibody-drug conjugate in which a drug represented by the formula is linked to an antibody via a linker; a method for measuring the concentration of the antibody-drug conjugate in the plasma of a mammal dosed with the antibody-drug conjugate using the protein; and a method for checking the tissue distribution of the antibody-drug conjugate in the mammal using the protein.