GIP/GLP1 co-agonist compounds
The present invention relates to compounds having activity at both the human glucose-dependent insulinotropic polypeptide (GIF) and glucagon-like peptide-1 (GLP-1) receptors. The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore...
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| creator | WALLIS, James Lincoln ABURUB, Aktham BROWN, Robert Andrew SLOOP, Kyle Wynn ABRAHAM, Milata Mary ELSAYED, Mohamed ElSayed Hamed PATEL, Phenil Jayantilal TRAN, Thi Thanh Huyen QU, Hongchang CUMMINS, Robert Chadwick WILLARD, Francis Stafford CABRERA, Over DATTA-MANNAN, Amita ALSINA-FERNANDEZ, Jorge LAI, Xianyin COSKUN, Tamer |
| description | The present invention relates to compounds having activity at both the human glucose-dependent insulinotropic polypeptide (GIF) and glucagon-like peptide-1 (GLP-1) receptors. The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore, the present invention relates to compounds that may be administered orally. Compounds may be useful in the treatment of type 2 diabetes mellitus ("T2DM"). Also, the compounds may be useful in the treatment of obesity. |
| format | Patent |
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The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore, the present invention relates to compounds that may be administered orally. Compounds may be useful in the treatment of type 2 diabetes mellitus ("T2DM"). 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The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore, the present invention relates to compounds that may be administered orally. Compounds may be useful in the treatment of type 2 diabetes mellitus ("T2DM"). Also, the compounds may be useful in the treatment of obesity.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | GIP/GLP1 co-agonist compounds |
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