Methods of de-epitoping wheat proteins and use of same for the treatment of celiac disease

A method for identifying an epitope of a wheat T cell immunogen is provided. The method comprises identifying an epitope on the wheat T cell immunogen for the ability to bind a major histocompatibility complex (MHC) class II, thereby identifying the epitope of a wheat T cell immunogen.

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Bibliographische Detailangaben
Hauptverfasser:	ZAKIN, Shiri, OFRAN, Yanay, BIRAN, Assaf, MARCU, Orly, BEN-DAVID, Moshe
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW PLANTS OR PROCESSES FOR OBTAINING THEM ORGANIC CHEMISTRY PEPTIDES PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method for identifying an epitope of a wheat T cell immunogen is provided. The method comprises identifying an epitope on the wheat T cell immunogen for the ability to bind a major histocompatibility complex (MHC) class II, thereby identifying the epitope of a wheat T cell immunogen.