Compounds for the treatment of seizures and other central nervous system disorders and conditions

The present application relates to novel compounds comprising a moiety that leads to the metabolic production of ketones bonded to a ketone- potentiated anti-epileptic drug, compositions comprising these compounds, and their use, for example for the treatment of epilepsy, and other CNS diseases, dis...

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Bibliographische Detailangaben
Hauptverfasser: Estey, Paula J, Nagireddy, Jaipal R, Robinson, Gary L.W.G, Araujo, Joseph A, Higgins, Guy A, Milgram, Norton W, Andrews, John S, Annedi, Subhash C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present application relates to novel compounds comprising a moiety that leads to the metabolic production of ketones bonded to a ketone- potentiated anti-epileptic drug, compositions comprising these compounds, and their use, for example for the treatment of epilepsy, and other CNS diseases, disorders or conditions. In particular, the present application includes compounds of Formula I, and compositions and uses thereof: