IMAGING NEUROLOGICAL DISEASE

C:\Interwo n\NRPortbl\DCC\SXD\19370605_l.docx-23/l0/2019 The present invention relates to radiopharmaceutical imaging of the brain, in particular to dopamine transporter imagining of the striatum (or a portion thereof). A 5 method of imaging to permit calculation of left: right striatum uptake ratios is provided, and the degree of asymmetry used to assist in the diagnosis of neurological diseases. Also provided are a method of diagnosis, method of patient selection, and method of therapy monitoring using the imaging method, and software tools for use in the method. WO 2015/011267 PCT/EP2014/066042 Figure 1: SBR Ratio (Prior Art). Striatum (Right and Left) 0 20 40 60 80 100 Age Figure 2: striatum R/L ratio Striatum R/L 0 20 40 60 80 100 Age