COMPOSITIONS, SYSTEMS, KITS, AND METHODS FOR NEURAL ABLATION
Abstract Accordingly, provided herein are methods for ameliorating pain in a subject in need thereof. The methods can comprise inserting an introducer cannula into the subject and positioning a distal end of the introducer cannula proximate a treatment site comprising a nerve that transmits a pain i...
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| creator | WASHINGTON, Alencia V LAVIGNE, Mark SMITH, Michael G ALAS, Guillermo ADESINA, Sherry E |
| description | Abstract Accordingly, provided herein are methods for ameliorating pain in a subject in need thereof. The methods can comprise inserting an introducer cannula into the subject and positioning a distal end of the introducer cannula proximate a treatment site comprising a nerve that transmits a pain impulse; advancing an ablation probe through the introducer to a region proximate to the treatment site; ablating the nerve with the ablation probe, thereby forming a lesion on the nerve; retracting the ablation probe; and injecting a liquid composition through the introducer cannula and into the treatment site. Following injection, the liquid composition can form a polymeric matrix at the treatment site. Preloaded syringe Storage temp (liquid) Injection temp (liquid) Administer after RF Polyrmer coats Gel sets Biodegrades/bioabsorbs ablation site (physical barrier) Test Concept Polymer can be dispensed through various introducer manifestations |
| format | Patent |
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The methods can comprise inserting an introducer cannula into the subject and positioning a distal end of the introducer cannula proximate a treatment site comprising a nerve that transmits a pain impulse; advancing an ablation probe through the introducer to a region proximate to the treatment site; ablating the nerve with the ablation probe, thereby forming a lesion on the nerve; retracting the ablation probe; and injecting a liquid composition through the introducer cannula and into the treatment site. Following injection, the liquid composition can form a polymeric matrix at the treatment site. Preloaded syringe Storage temp (liquid) Injection temp (liquid) Administer after RF Polyrmer coats Gel sets Biodegrades/bioabsorbs ablation site (physical barrier) Test Concept Polymer can be dispensed through various introducer manifestations</description><language>eng</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS ; DIAGNOSIS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; IDENTIFICATION ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORGANIC MACROMOLECULAR COMPOUNDS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SURGERY ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200430&DB=EPODOC&CC=AU&NR=2019250128A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200430&DB=EPODOC&CC=AU&NR=2019250128A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WASHINGTON, Alencia V</creatorcontrib><creatorcontrib>LAVIGNE, Mark</creatorcontrib><creatorcontrib>SMITH, Michael G</creatorcontrib><creatorcontrib>ALAS, Guillermo</creatorcontrib><creatorcontrib>ADESINA, Sherry E</creatorcontrib><title>COMPOSITIONS, SYSTEMS, KITS, AND METHODS FOR NEURAL ABLATION</title><description>Abstract Accordingly, provided herein are methods for ameliorating pain in a subject in need thereof. The methods can comprise inserting an introducer cannula into the subject and positioning a distal end of the introducer cannula proximate a treatment site comprising a nerve that transmits a pain impulse; advancing an ablation probe through the introducer to a region proximate to the treatment site; ablating the nerve with the ablation probe, thereby forming a lesion on the nerve; retracting the ablation probe; and injecting a liquid composition through the introducer cannula and into the treatment site. Following injection, the liquid composition can form a polymeric matrix at the treatment site. 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The methods can comprise inserting an introducer cannula into the subject and positioning a distal end of the introducer cannula proximate a treatment site comprising a nerve that transmits a pain impulse; advancing an ablation probe through the introducer to a region proximate to the treatment site; ablating the nerve with the ablation probe, thereby forming a lesion on the nerve; retracting the ablation probe; and injecting a liquid composition through the introducer cannula and into the treatment site. Following injection, the liquid composition can form a polymeric matrix at the treatment site. Preloaded syringe Storage temp (liquid) Injection temp (liquid) Administer after RF Polyrmer coats Gel sets Biodegrades/bioabsorbs ablation site (physical barrier) Test Concept Polymer can be dispensed through various introducer manifestations</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DIAGNOSIS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE IDENTIFICATION MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SURGERY THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | COMPOSITIONS, SYSTEMS, KITS, AND METHODS FOR NEURAL ABLATION |
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