COMPOSITIONS, SYSTEMS, KITS, AND METHODS FOR NEURAL ABLATION

Abstract Accordingly, provided herein are methods for ameliorating pain in a subject in need thereof. The methods can comprise inserting an introducer cannula into the subject and positioning a distal end of the introducer cannula proximate a treatment site comprising a nerve that transmits a pain impulse; advancing an ablation probe through the introducer to a region proximate to the treatment site; ablating the nerve with the ablation probe, thereby forming a lesion on the nerve; retracting the ablation probe; and injecting a liquid composition through the introducer cannula and into the treatment site. Following injection, the liquid composition can form a polymeric matrix at the treatment site. Preloaded syringe Storage temp (liquid) Injection temp (liquid) Administer after RF Polyrmer coats Gel sets Biodegrades/bioabsorbs ablation site (physical barrier) Test Concept Polymer can be dispensed through various introducer manifestations