Factor XIIa inhibitors

This invention relates to compoundsof formula (I)and methods of treatment using the compounds. The invention also relates to processes and methods for producing the compounds of the invention. The compounds of the invention are modulators of Factor XII (e.g. Factor XIIa). In particular, the compound...

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Bibliographische Detailangaben
Hauptverfasser: NAYLOR, Alan, STEWART, Mark Richard, REVILL, Charlotte, TAYLOR, Roger, MACNAIR, Alistair James, FOSTER, Richard, WINFIELD, Natalie Louise, CROSBY, Stuart, FALLON, Philip Spencer, PHILIPPOU, Helen, HOPKINS, Anna, YULE, Ian, FISHWICK, Colin, GUETZOYAN, Lucie Juliette
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to compoundsof formula (I)and methods of treatment using the compounds. The invention also relates to processes and methods for producing the compounds of the invention. The compounds of the invention are modulators of Factor XII (e.g. Factor XIIa). In particular, the compounds are inhibitors of Factor XIIa and may be useful as anticoagulants.