SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS

SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS

A pharmaceutical composition comprising toluenesulfonic acid and the compound of Formula 2J: R9 k N R5 R8H R*) (S* )M R6 a R6 b 5 Formula 2J or a pharmaceutically acceptable salt thereof, wherein: (i) k is 1; (ii) m is 1; (iii) n is 1; 10 (iv) RI is 4-(4-fluorophenyl)-4-oxobutyl; (v) R is H; (vi) R6...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Peng, Tomesch, John Charles, Zhang, Qiang, Thompson, Andrew S
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A pharmaceutical composition comprising toluenesulfonic acid and the compound of Formula 2J: R9 k N R5 R8H R*) (S* )M R6 a R6 b 5 Formula 2J or a pharmaceutically acceptable salt thereof, wherein: (i) k is 1; (ii) m is 1; (iii) n is 1; 10 (iv) RI is 4-(4-fluorophenyl)-4-oxobutyl; (v) R is H; (vi) R6a and R 6 are independently H; (vii) R', R8 and R9 are independently H; (viii) R10 is CH3; and 15 (ix) X is -N-.