Thiophene derivative and use thereof
The present invention relates to a thiophene derivative represented by general formula (I) (wherein each symbol is as defined in the description) or a salt thereof, which has an activity to prevent the production of TNF-α and an activity to prevent the proliferation of a hematological cancer cell, a...
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| creator | WATANABE, Mayumi ISHII, Takafumi YAMADA, Mitsuo MATSUSHITA, Kenya ANDO, Takashi URABE, Kazunori MIZUTANI, Yasuhiko KANAOKA, Daiki UEDA, Yasuyuki TAKAHASHI, Jun YOKOYAMA, Hironori |
| description | The present invention relates to a thiophene derivative represented by general formula (I) (wherein each symbol is as defined in the description) or a salt thereof, which has an activity to prevent the production of TNF-α and an activity to prevent the proliferation of a hematological cancer cell, and is useful for the treatment of rheumatoid arthritis, Crohn's disease, ulcerative colitis and hematological cancer. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Thiophene derivative and use thereof |
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