MULTI-UNIT DRUG DELIVERY DEVICES AND METHODS

Implantable drug delivery devices include a housing defining a reservoir, a first unit within the reservoir, and a second unit within the reservoir. The first unit contains a drug and the second unit contains a functional agent that facilitates release of the drug. Intravesical drug delivery devices...

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Bibliographische Detailangaben
Hauptverfasser: Sansone, Matthew, Lee, Heejin, Daniel, Karen
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Implantable drug delivery devices include a housing defining a reservoir, a first unit within the reservoir, and a second unit within the reservoir. The first unit contains a drug and the second unit contains a functional agent that facilitates release of the drug. Intravesical drug delivery devices include a housing portion containing a drug formulation and a housing portion containing an excipient, and are configured to release the drug according to a first release profile and the excipient according to a second release profile. Methods include inserting any of these devices into a patient and releasing drug from the device. WO 2015/026813 PCT/US2014/051672 A-100 104 102 102 102 102 102 102 102 102 102 102 102 102 102 102 102 -200 210 210 210 210 202 202 202 tIJW 2404 A ::r206 208 210 210 210 210 210 202 202 202 306 g- 300 310 310 302 302 302 310 310 308 310 310 310 302 302 310 310 310 r- 400 410 410 410 410 S¶/4 410 410410410 410 402