Small molecule inhibitors of EGFR and PI3K

SMALL MOLECULE INHIBITORS OF EGFR AND P13K This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and P13K proteins, and t...

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Bibliographische Detailangaben
Hauptverfasser: WHITEHEAD, Christopher Emil, LEOPOLD, Judith S
Format: Patent
Sprache:eng
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Zusammenfassung:SMALL MOLECULE INHIBITORS OF EGFR AND P13K This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and P13K proteins, and their use as therapeutics for the treatment of cancer and other diseases.