Bicyclic aza compounds as muscarinic M1 receptor and/or M4 receptor agonists
Abstract This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the 5 compounds and the therapeutic uses of t...
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| creator | Tehan, Benjamin Gerald O'Brien, Michael Alistair Cansfield, Julie Elaine Teobold, Barry John Brown, Giles Albert Pickworth, Mark Rackham, Mark David Congreve, Miles Stuart |
| description | Abstract This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the 5 compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1 R (1) or a salt thereof, wherein Q, R 1, R2, R3 and R4 are as defined herein. |
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Also provided are pharmaceutical compositions containing the 5 compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1 R (1) or a salt thereof, wherein Q, R 1, R2, R3 and R4 are as defined herein.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200827&DB=EPODOC&CC=AU&NR=2019201579B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200827&DB=EPODOC&CC=AU&NR=2019201579B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Tehan, Benjamin Gerald</creatorcontrib><creatorcontrib>O'Brien, Michael Alistair</creatorcontrib><creatorcontrib>Cansfield, Julie Elaine</creatorcontrib><creatorcontrib>Teobold, Barry John</creatorcontrib><creatorcontrib>Brown, Giles Albert</creatorcontrib><creatorcontrib>Pickworth, Mark</creatorcontrib><creatorcontrib>Rackham, Mark David</creatorcontrib><creatorcontrib>Congreve, Miles Stuart</creatorcontrib><title>Bicyclic aza compounds as muscarinic M1 receptor and/or M4 receptor agonists</title><description>Abstract This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Bicyclic aza compounds as muscarinic M1 receptor and/or M4 receptor agonists |
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