Bicyclic aza compounds as muscarinic M1 receptor and/or M4 receptor agonists

Abstract This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the 5 compounds and the therapeutic uses of t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Tehan, Benjamin Gerald, O'Brien, Michael Alistair, Cansfield, Julie Elaine, Teobold, Barry John, Brown, Giles Albert, Pickworth, Mark, Rackham, Mark David, Congreve, Miles Stuart
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Abstract This invention relates to compounds that are agonists of the muscarinic M1 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the 5 compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1 R (1) or a salt thereof, wherein Q, R 1, R2, R3 and R4 are as defined herein.