Cape-loaded targeted micro vesicular cancer drug and method for developing the same

The present invention relates to production of a drug which is specific for SH- SY5Y neuroblastoma cancer by loading CAPE to microvesicles that the specialized skin cell leaves into the nutrient solution. The objective of the present invention is to provide a cell-specific targeted vesicle developme...

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Bibliographische Detailangaben
Hauptverfasser:	APDIK, Huseyin, TASLI, Pakize Neslihan, AVSAR APDIK, Ezgi, KIRBAS, Oguz Kaan, SAHIN, Fikrettin
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to production of a drug which is specific for SH- SY5Y neuroblastoma cancer by loading CAPE to microvesicles that the specialized skin cell leaves into the nutrient solution. The objective of the present invention is to provide a cell-specific targeted vesicle development by loading CAPE to the microvesicles obtained as a result of the culturing and subsequent specialization (differentiation) of the tissue cells; and to use CAPE at lower concentrations compared to the state of the art applications to minimize its toxicity to both the cells other than the targeted cells and the body.