Macrocyclic immunomodulators

Macrocyclic immunomodulators

Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with prep...

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Bibliographische Detailangaben
Hauptverfasser: PUNNA, Sreenivas, MCMURTRIE, Darren J, ROTH, Howard S, SINGH, Rajinder, ZHANG, Penglie, MALATHONG, Viengkham, MCMAHON, Jeffrey
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.