Methods and compositions for reducing the immunogenicity of chimeric notch receptors

The present invention relates to methods and compositions for reducing the immunogenicity of chimeric Notch receptors, and specifically to transcription factors useful for controlling gene expression delivered to tissues by such chimeric Notch receptors.

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Bibliographische Detailangaben
Hauptverfasser: Gilbert, Amy, Slepushkin, Vladimir, Scott, Spencer, Emtage, Peter, Levskaya, Anselm
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods and compositions for reducing the immunogenicity of chimeric Notch receptors, and specifically to transcription factors useful for controlling gene expression delivered to tissues by such chimeric Notch receptors.