Bispecific heterodimeric diabodies and uses thereof

Bispecific heterodimeric diabodies and uses thereof

BISPECIFIC HETERODIMERIC DIABODIES AND USES THEREOF Abstract Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadhe...

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Leslie S, May, Chad Michael, Mosyak, Lidia, Root, Adam Reid, Tchistiakova, Lioudmila Gennadievna, Bloom, Laird, Brady, William A, Moore, Paul A
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Zusammenfassung:BISPECIFIC HETERODIMERIC DIABODIES AND USES THEREOF Abstract Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadherin tumor cell associated antigen and the CD3 T cell antigen.