Variants of human BMP7 protein

The present invention relates to novel variants of human BMP7 protein. The invention embodies vectors and host cells for the propagation of nucleic acid sequences encoding said proteins and the production thereof. Also disclosed are methods for the treatment of cancer, cartilage damage and degenerat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rowlinson, Scott William, Stancato, Louis Frank, Pancook, James David
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel variants of human BMP7 protein. The invention embodies vectors and host cells for the propagation of nucleic acid sequences encoding said proteins and the production thereof. Also disclosed are methods for the treatment of cancer, cartilage damage and degeneration, pain associated with osteoarthritis, or bone healing.