Liquid crystalline dosage form for administering a statin

A composition including an amphiphilic compound capable of self-assembling into liquid crystalline particles and a statin for systemic administration via oral mucosa. A method of lowering blood cholesterol levels in a subject comprising administering the self-assembling liquid crystalline particles...

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Bibliographische Detailangaben
Hauptverfasser: Kannar, David, Szto, Gregory Yu Foo, Madmon, Tomer
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A composition including an amphiphilic compound capable of self-assembling into liquid crystalline particles and a statin for systemic administration via oral mucosa. A method of lowering blood cholesterol levels in a subject comprising administering the self-assembling liquid crystalline particles and statin via oral mucosa. Preferred dosage forms result in prolonged release of the statin.