C4BP-based compounds for treating immunological diseases

The invention relates to compounds for use in the prevention and/or treatment of immunological diseases, particularly rheumatoid arthritis systemic lupus erythematosus and lupus nephritis, characterized by the subcutaneous administration of isoforms of C4BP lacking the beta chain or polypeptides com...

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Bibliographische Detailangaben
Hauptverfasser: Ortiz Sagristà, Jordi, Ruiz Ávila, Luis Antonio, Aran Perramon, Josep M, Lluch Lafuente, Nuria
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to compounds for use in the prevention and/or treatment of immunological diseases, particularly rheumatoid arthritis systemic lupus erythematosus and lupus nephritis, characterized by the subcutaneous administration of isoforms of C4BP lacking the beta chain or polypeptides comprising the CCP6 region of the alpha chain of C4BP no more than once a week or at a dose ranging from 0.24 mg/m