Stable Liquid Formula

A stable liquid formula according to the present invention comprises an antibody or an antigen-binding fragment thereof; an acetate buffer; glycine; and a surfactant, without inclusion of one or more of a saccharide, a sugar alcohol, and a metal salt, is stable even at a high content of an antibody...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Su Jung, Oh, Jun Seok, Kim, Kwang Woo, Shin, Yeon Kyeong, Kang, Hye Young, Han, Won Yong, Lee, Joon Won, Kim, So Young
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A stable liquid formula according to the present invention comprises an antibody or an antigen-binding fragment thereof; an acetate buffer; glycine; and a surfactant, without inclusion of one or more of a saccharide, a sugar alcohol, and a metal salt, is stable even at a high content of an antibody and superior in terms of osmolality and viscosity, and can be administered subcutaneously.