Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors

Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors

Abstract The present invention provides compounds of formula (1) o=s=o NR4 () which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.

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Bibliographische Detailangaben
Hauptverfasser: CULSHAW, Andrew James, HOLLINGWORTH, Gregory, WATSON, Simon James, BRUCE, Ian, NEEF, James, SPENDIFF, Matthew, BELLENIE, Benjamin Richard, BLOOMFIELD, Graham Charles, HALL, Edward Charles
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Abstract The present invention provides compounds of formula (1) o=s=o NR4 () which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform.