Muscle performance improvement compounds

A compound comprising at least two components, a first component being the nLG3 domain from the C-terminus of human agrin, and at least one second component, selected from proteins or an antagonistic antibody that inhibit ActR2B-induced signaling activity in the presence of myostatin, the components...

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Bibliographische Detailangaben
Hauptverfasser: Boido, Marina Maria, Schellino, Roberta, Vrijbloed, Jan Willem, Butenko, Olena
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A compound comprising at least two components, a first component being the nLG3 domain from the C-terminus of human agrin, and at least one second component, selected from proteins or an antagonistic antibody that inhibit ActR2B-induced signaling activity in the presence of myostatin, the components being linked by means of linking entities. Such compounds are effective treatments for neuromuscular diseases and problems.