Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof

Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof

The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X", Z

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Bibliographische Detailangaben
Hauptverfasser: Cunningham, Richard, Erickson, Aron, Redpath, Philip, Nygaard, Richard, Migaud, Marie Eugenie, Crossey, Kerri, Storjohann, Amanda
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Beschreibung
Zusammenfassung:The present disclosure provides methods of making nicotinoyl riboside compounds or derivatives of formula (I): wherein X", Z