Canine adenovirus vectors

The present invention relates to the field of CAdV vector vaccines, and especially to promoters suitable to express target antigens from such vector vaccines. Disclosed and claimed are recombinant canine adenoviruses, methods of making them, uses for them (including in immunological, immunogenic, va...

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Bibliographische Detailangaben
Hauptverfasser: Rehmet, Kristina, Koukuntla, Ramesh, Vaughn, Eric Martin, Gallei, Andreas, Mundt, Alice, Mandell, Robert Barry
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to the field of CAdV vector vaccines, and especially to promoters suitable to express target antigens from such vector vaccines. Disclosed and claimed are recombinant canine adenoviruses, methods of making them, uses for them (including in immunological, immunogenic, vaccine or therapeutic compositions, or, as a vector for cloning, replicating or expressing DNA and methods of using the compositions and vector), expression products from them, and uses for the expression products. Additionally, disclosed and claimed are truncated EHV4 promoters, expression cassettes containing the promoters, and recombinant viruses and plasmids containing the promoters or expression cassettes.