TRPV4 antagonists

The present invention relates to pyrrolidine sulfonamide analogs (I), pharmaceutical compositions containing them and their use as TRPV4 antagonists.

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Bibliographische Detailangaben
Hauptverfasser:	Li, Peng, Pero, Joseph E, Matthews, Jay M, Lawhorn, Brian Griffin, Sender, Matthew Robert, Behm, David J, Brooks, Carl A, Mcatee, John Jeffrey, Brnardic, Edward J, Terrell, Lamont Roscoe
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to pyrrolidine sulfonamide analogs (I), pharmaceutical compositions containing them and their use as TRPV4 antagonists.