Nalmefene, naltrexone or derivatives thereof for use in treating (non)-alcoholic steatohepatitis or non-alcoholic fatty liver disease

The present invention relates to morphinans selected from nalmefene and naltrexone and their related derivatives of formula (I), and pharmaceutical formulations thereof, for use in the prevention and treatment of NASH, NAFLD, and/or ASH.

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Bibliographische Detailangaben
Hauptverfasser: Chiu, Peter J. S, Wu, Edwin S. C, Hsu, May Mei-chi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to morphinans selected from nalmefene and naltrexone and their related derivatives of formula (I), and pharmaceutical formulations thereof, for use in the prevention and treatment of NASH, NAFLD, and/or ASH.