Compositions and Methods for Non-Toxic Delivery of Antiprogestins

Compositions and Methods for Non-Toxic Delivery of Antiprogestins

A method for treating a progesterone-dependent condition selected from the group consisting of endometriosis and pain associated therewith, adenomyosis, endometriosis or pain associated therewith, dysmenorrhea, uterine fibroids, endometrial hyperproliferation, ovarian cancer, and cervical cancer com...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WIEHLE, Ronald D, PODOLSKI, Joseph S
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Beschreibung
Zusammenfassung:A method for treating a progesterone-dependent condition selected from the group consisting of endometriosis and pain associated therewith, adenomyosis, endometriosis or pain associated therewith, dysmenorrhea, uterine fibroids, endometrial hyperproliferation, ovarian cancer, and cervical cancer comprising daily administration of a composition comprising between 5 and 20 mg of 21 - methoxy- 17a-acetoxy- 11p-(4 N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20 dione or 17a-acetoxy-11p-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-dien-3,20-dione locally to the vaginal mucosa of a female in need thereof for period of at least 4 months.