The use of a hemocompatible porous polymer bead sorbent for removal of pamps and damps

The invention concerns biocompatible polymer systems comprising at least one polymer sorbent with a plurality of pores, said polymer designed to adsorb pathogen-associated molecular pattern molecules and damage-associated molecular pattern molecules. Also disclosed herein are methods for reducing co...

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Bibliographische Detailangaben
Hauptverfasser: Scheirer, Andrew, Chan, Phillip, Capponi, Vincent, O'Sullivan, Pamela, Gruda, Maryann, Golobish, Thomas, Guliashvili, Tamaz
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention concerns biocompatible polymer systems comprising at least one polymer sorbent with a plurality of pores, said polymer designed to adsorb pathogen-associated molecular pattern molecules and damage-associated molecular pattern molecules. Also disclosed herein are methods for reducing contamination in a biological substance, or treating contamination in a subject, by one or more pathogen-associated molecular pattern molecules and damage-associated molecular pattern molecules, by contacting the biological substance with an effective amount of sorbent capable of sorbing the toxin.