HOST CELLS AND METHODS FOR PRODUCTION OF ISOBUTANOL

Provided herein are recombinant yeast host cells and methods for their use for production of isobutanol. Yeast host cells provided comprise 5 an isobutanol biosynthetic pathway and at least one of reduced or eliminated aldehyde dehydrogenase activity, reduced or eliminated acetolactate reductase act...

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Bibliographische Detailangaben
Hauptverfasser:	McELVAIN, Jessica, HE, Hongxian, ROTHMAN, Steven Cary, HUANG, Lisa L, LI, Yougen, ANTHONY, Larry Cameron, NELSON, Mark J, GIBSON, Katharine J, MAGGIO-HALL, Lori Ann, KRUCKEBERG, Arthur Leo, PATNAIK, Ranjan, O'KEEFE, Daniel P
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are recombinant yeast host cells and methods for their use for production of isobutanol. Yeast host cells provided comprise 5 an isobutanol biosynthetic pathway and at least one of reduced or eliminated aldehyde dehydrogenase activity, reduced or eliminated acetolactate reductase activity; or a heterologous polynucleotide encoding a polypeptide having ketol-acid reductoisomerase activity.