Multivariate diagnostic assays and methods for using same

The application describes compositions and methods for detecting the relative expressions of a plurality of target nucleic acid molecules in one assay. The compositions comprise a plurality of probe molecules which specifically bind to one target nucleic acid molecule of a plurality of target nuclei...

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Hauptverfasser: Storhoff, James Justin, Wallden, Brett, Geiss, Gary K, Ferree, Sean M, Webster, Philippa Jane, Payandeh, Emily
Format: Patent
Sprache:eng
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Zusammenfassung:The application describes compositions and methods for detecting the relative expressions of a plurality of target nucleic acid molecules in one assay. The compositions comprise a plurality of probe molecules which specifically bind to one target nucleic acid molecule of a plurality of target nucleic acids in a sample, and a plurality of reference molecules that represent each of the plurality of target nucleic acid molecules, where the probe molecules specifically bind to the plurality of reference molecules, and each of the plurality of reference molecules is present in known amounts in the composition.