System and method for in situ visualization of nerves using targeted fluorescent molecules

The present invention is directed to a system and method for enhancing in situ visualization of a target site within a patient during a medical procedure using fluorescence. As such, the system includes a plurality of fluorescent molecules (12) configured to selectively target and bind to one or more locations at the target site (16) within the patient and a delivery mechanism (20) for delivering the fluorescent molecules into the patient. In addition, the system includes a detection device (26) configured to generate a detectable signal containing information relating to the target site and send the detectable signal to an imaging system for viewing by a user, such as a physician. Thus, the fluorescent molecules enhance in situ visualization of the target site when viewed through the skin of the patient.