Variable regions for NKp46 binding proteins

Variable regions for NKp46 binding proteins

NKp46-binding immunoglobulin variable regions, and proteins such as antibodies and multispecific proteins that comprise the variable regions are provided. The proteins can bind and specifically redirect NK cells to lyse a target cell of interest. The proteins have utility in the treatment of disease...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gauthier, Laurent, Morel, Ariane, Anceriz, Nadia, Rossi, Benjamin
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
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ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:NKp46-binding immunoglobulin variable regions, and proteins such as antibodies and multispecific proteins that comprise the variable regions are provided. The proteins can bind and specifically redirect NK cells to lyse a target cell of interest. The proteins have utility in the treatment of disease, notably cancer or infectious disease.