2-Aminoquinazoline derivatives as p70S6 kinase inhibitors

2-Aminoquinazoline derivatives as p70S6 kinase inhibitors

The invention provides compound that inhibit or modulate the activity of p70S6 kinase, the compounds being of the formula (I) or a salt, tautomer or N-oxide thereof; wherein: one of Y and Z is R

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Bibliographische Detailangaben
Hauptverfasser: Walker, David Winter, Boyle, Robert George
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides compound that inhibit or modulate the activity of p70S6 kinase, the compounds being of the formula (I) or a salt, tautomer or N-oxide thereof; wherein: one of Y and Z is R