Perfusion manifold assembly

Drop-to-drop connection schemes are described for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly. A perfusion manifold...

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Bibliographische Detailangaben
Hauptverfasser: Potzner, Christian Alexander, Gomes, Joshua, Freake, Jacob, Solomon, Matthew Daniel, Hinojosa, Christopher David, Sliz, Josiah Daniel, Tuohy, Patrick Sean, Thompson II, Guy Robert, Sabin, Doug, Levner, Daniel, Wen, Norman, Martinus Van Ruijven, Petrus
Format: Patent
Sprache:eng
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Zusammenfassung:Drop-to-drop connection schemes are described for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly. A perfusion manifold assembly is described that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.