Textured articles for enhanced cell formation and methods of making thereof

Disclosed herein is an article including a substrate having at least one surface that has a texture and a first type of growing cells, wherein an average length of features that form the texture is operative to facilitate cell growth, cell orientation, cell morphology and cell differentiation. Disclosed herein too is a method including forming a first layer of a polymeric material on at least one surface of a substrate; texturing the first layer to form a textured first layer; and forming a first type of growing cells on the textured first layer, wherein an average length of features that form the textured first layer is operative to facilitate cell growth, cell orientation, cell morphology and cell differentiation.