GLS1 inhibitors for treating disease

Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided.

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Hauptverfasser: Lewis, Richard Thomas, Reyna, Naphtali, Han, Michelle, Heffernan, Timothy, Jones, Philip, Hamilton, Matthew, Soth, Michael J, Petrocchi, Alessia, Burke, Jason P
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creator Lewis, Richard Thomas
Reyna, Naphtali
Han, Michelle
Heffernan, Timothy
Jones, Philip
Hamilton, Matthew
Soth, Michael J
Petrocchi, Alessia
Burke, Jason P
description Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title GLS1 inhibitors for treating disease
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