GLS1 inhibitors for treating disease

Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided.

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Bibliographische Detailangaben
Hauptverfasser:	Lewis, Richard Thomas, Reyna, Naphtali, Han, Michelle, Heffernan, Timothy, Jones, Philip, Hamilton, Matthew, Soth, Michael J, Petrocchi, Alessia, Burke, Jason P
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disclosed herein are compounds and compositions useful in the treatment of GLSl mediated diseases, such as cancer, having the structure of Formula (I). Methods of inhibition GLSl activity in a human or animal subject are also provided.