Novel CRISPR enzymes and systems

The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non -naturally occurring or engineered DNA or RNA- targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic aci...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wolf, Yuri I, Shmakov, Sergey, Semenova, Ekaterina, Koon, Eugene, Zhang, Feng, Konermann, Silvana, Abudayyeh, Omar O, Minakhin, Leonid, Joung, Julia, Gootenberg, Jonathan S, Severinov, Konstantin, Makarova, Kira S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non -naturally occurring or engineered DNA or RNA- targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.