Devices and methods for sample analysis

Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Holets-Mccormack, Shelley R, Huff, Jeffrey B, Hayden, Mark A, Fischer, Andrew (Andy), Robinson, John M, Karabatsos, Peter J, Laurenson, Sophie
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.