Processes and intermediates for preparing a macrocyclic protease inhibitor of HVC

Processes and intermediates for preparing a macrocyclic protease inhibitor of HVC

Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.

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Bibliographische Detailangaben
Hauptverfasser: Moody, Thomas Shaw, Hermant, Sebastien Nicolas J, Ormerod, Dominic John, Horvath, Andras, Depre, Dominique Paul Michel, Riant, Olivier, Brossat, Maude, Lemaire, Sebastien Francois Emmanuel, Vriamont, Nicolas
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.